Acute Inhalation Injury
Dr. Nur Şafak ALICI


Acute inhalation injury; is a nonspecific definition that refers to the damage of the respiratory tract and lung tissue due to various forms of inhaled irritant, toxic substances and thermal effect to the inhaled smoke. These substances enter the body through inhalation in the form of gaseous or suspended solid (dust) or liquid (aerosol). They can act with different mechanisms. They may cause local and irritant or systemic toxic effects (1). These effects are depends on the chemical structure, diameter and water solubility of the material being exposed. They can cause pulmonary epithelial damage at different levels of the respiratory system, they can cause asphyxia or systemic effects by systemic absorption. With irritation and direct damage; clinical manifestations may seen at all levels, such as rhinitis, tracheitis, bronchitis, bronchiolitis, alveoilitis, etc. In addition, systemic toxins such as carbon monoxide and cyanide may interfere with the uptake or use of oxygen in the body. As a result, inhalation injury occurs with pulmonary irritation, asphyxia (simple, chemical) and thermal damage involving the upper airways. Although the acute inhalation injury usually presented with a quick recovery, it may cause long-term complications and even death.

Keywords: Toxic inhalation, fume, dust, alveolar damage, occupational exposure
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